Gonadorelin Peptide
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Targeted Endocrine & Reproductive Signaling Research Gonadorelin (GnRH Synthetic Peptide) A high-purity synthetic peptide structurally identical to endogenous Gonadotropin-Releasing Hormone (GnRH). Designed to precisely stimulate the secretion of LH and FSH, making it an essential reference compound for reproductive endocrinology, axis regulation, and hormone receptor binding studies.
Key Highlights
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Endogenous Sequence Homology: Matches natural hypothalamic GnRH, ensuring precise receptor binding and predictable biological signaling in research models.
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Dual Gonadotropin Stimulation: Promotes the downstream release of both Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) from the anterior pituitary gland.
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Endocrine Axis Reference Standard: Highly utilized for studying the hypothalamic-pituitary-gonadal (HPG) axis, receptor desensitization, and feedback loop kinetics.
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High Chemical Stability: Manufactured via precision solid-phase peptide synthesis (SPPS) for optimal purity, solubility, and batch-to-batch consistency.
Mechanism of Action
Gonadorelin acts as a direct agonist at the GnRH receptors located on pituitary gonadotropes:
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Receptor Binding: Binds to specific G-protein coupled receptors (GPCRs) on gonadotropic cells in the anterior pituitary.
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Signal Transduction: Triggers intracellular calcium release and protein kinase C (PKC) activation pathways.
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Hormone Secretion: Induces pulsatile release of LH and FSH into circulation, stimulating downstream steroidogenesis and gametogenesis pathways.
Keep lyophilized peptides sealed in their original vial, protected from light and humidity, and store at -4°F or colder for optimal long-term stability in research settings; short-term refrigeration at around 39°F suffices for immediate use within weeks, though freezer storage maximizes integrity across extended research timelines.
Frequently Asked Questions
How isshipped?
Orders are processed and shipped using secure, protective packaging to maintain product integrity during transit.
In what form is supplied?
Shipment is available in freeze-dried solid or liquid form.
How should be stored?
Store sealed vials protected from light, heat, and contamination in a clean laboratory environment.
What vial sizes are available ?
available in multiple vial sizes.
How to place an order?
Contact us via WhatsApp or email to get a quotation and place your order.
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