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PT-141 – Bremelanotide Peptide

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Targeted Melanocortin Receptor Agonist for Vitality & Wellness Research PT-141 (Bremelanotide) is a synthetic peptide analog designed to target central nervous system melanocortin receptors (specifically MC3R and MC4R). Unlike traditional systemic options, PT-141 acts directly on neural pathways to support research in libido modulation, sexual function, and neural signaling.

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Description

Key Highlights

  • Central Mechanism of Action: Works directly within the central nervous system via melanocortin pathways rather than acting on the vascular system.

  • Dual-Action Receptor Binding: Selectively activates MC3R and MC4R receptors to regulate neural circuits tied to sexual desire and arousal.

  • Broad Application Potential: Studied for both male and female sexual dysfunction models, including Hypoactive Sexual Desire Disorder (HSDD) and erectile dysfunction (ED).

  • High Chemical Stability: Formulated as a stable synthetic cyclic peptide with high biological potency and specificity.

Mechanism of Action

PT-141 (Bremelanotide) is a cyclic heptapeptide metabolite derived from Melanotan II that lacks the C-terminal amide group, offering enhanced receptor selectivity:

  1. CNS Receptor Activation: Binds to central melanocortin receptors (primarily MC4R) in the hypothalamus.

  2. Dopaminergic Modulation: Triggers the release of dopamine in key brain regions involved in reward pathways and sexual motivation.

  3. Downstream Response: Induces natural physiological arousal responses downstream through central neural stimulation rather than direct nitric oxide/vascular dilation.

Additional information
size
Storage & Handling

Keep lyophilized peptides sealed in their original vial, protected from light and humidity, and store at -4°F or colder for optimal long-term stability in research settings; short-term refrigeration at around 39°F suffices for immediate use within weeks, though freezer storage maximizes integrity across extended research timelines.

FAQ

Frequently Asked Questions

How isshipped?

Orders are processed and shipped using secure, protective packaging to maintain product integrity during transit.

Shipment is available in freeze-dried solid or liquid form.

Store sealed vials protected from light, heat, and contamination in a clean laboratory environment.

available in multiple vial sizes.

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