Melanotan 1 Peptide
Contact us for quotation
Targeted Melanocortin Receptor Agonist for Sunless Tanning & UV Protection Research Melanotan I (MT-1 / Afamelanotide) is a synthetic analog of alpha-melanocyte-stimulating hormone ($\alpha$-MSH). Designed for selective MC1R receptor binding, it promotes controlled melanogenesis, enhances skin pigmentation research, and supports cellular photoprotection studies with high specificity.
Key Highlights
-
Selective MC1R Receptor Binding: Highly targeted agonist of the melanocortin-1 receptor (MC1R), primary responsible for stimulating eumelanin synthesis in melanocytes.
-
Stimulates Natural Pigmentation: Promotes dark melanin (eumelanin) production without requiring excessive UV exposure in research models.
-
Photoprotective Properties: Extensively studied for its ability to mitigate UV-induced DNA damage and reduce skin oxidative stress.
-
Refined Safety Profile: Offers greater MC1R selectivity compared to Melanotan II, resulting in minimal interaction with non-target melanocortin receptors (e.g., MC3R, MC4R).
Mechanism of Action
Melanotan I mimics the activity of endogenous $\alpha$-MSH across melanocortin receptors:
-
MC1R Activation: Binds to melanocortin-1 receptors on skin melanocytes, triggering cyclic AMP (cAMP) signaling pathways.
-
Tyrosinase Upregulation: Activates tyrosinase, the rate-limiting enzyme in melanin biosynthesis.
-
Eumelanin Production: Converts pheomelanin (red/yellow pigment) into eumelanin (brown/black pigment), building photoprotective pigmentation barriers.
| size | 10mg |
|---|
Keep lyophilized peptides sealed in their original vial, protected from light and humidity, and store at -4°F or colder for optimal long-term stability in research settings; short-term refrigeration at around 39°F suffices for immediate use within weeks, though freezer storage maximizes integrity across extended research timelines.
Frequently Asked Questions
How isshipped?
Orders are processed and shipped using secure, protective packaging to maintain product integrity during transit.
In what form is supplied?
Shipment is available in freeze-dried solid or liquid form.
How should be stored?
Store sealed vials protected from light, heat, and contamination in a clean laboratory environment.
What vial sizes are available ?
available in multiple vial sizes.
How to place an order?
Contact us via WhatsApp or email to get a quotation and place your order.
Related products
