B7-33 Peptide
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Targeted Metabolic & Cardiovascular Research (B7-33 Peptide) B7-33 is a novel, rationally designed single-chain relaxin receptor (RXFP1) agonist. Engineered as a non-fibrotic and non-mitogenic analog of relaxin-2, it provides targeted support for cardiovascular protection, tissue remodeling, and antifibrotic research.
Key Highlights
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Novel RXFP1 Agonist Design: A unique single-chain peptide engineered to selectively target the relaxin-2 receptor (RXFP1) without the structural complexity or mitogenic side effects of native relaxin.
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Antifibrotic & Tissue Remodeling Support: Extensively studied in scientific literature for its potential to reduce fibrosis and support tissue repair in cardiac and renal models.
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Cardiovascular Protection: Demonstrates cardioprotective properties by mitigating adverse cardiac remodeling, inflammation, and pressure overload effects.
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Clean Safety Profile in Vitro: Designed to avoid unwanted proliferative (mitogenic) activity commonly associated with earlier relaxin analogs.
Mechanism of Action
B7-33 operates through precise receptor engagement:
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RXFP1 Receptor Binding: Selectively targets and activates the relaxin family peptide receptor 1 (RXFP1).
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Downstream Signaling Modulation: Triggers specific signaling cascades (such as cAMP activation) that inhibit profibrotic pathways and extracellular matrix accumulation.
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Organ Protection: Promotes vascular relaxation, reduces collagen deposition, and supports recovery in stressed cardiac and organ tissues.
Keep lyophilized peptides sealed in their original vial, protected from light and humidity, and store at -4°F or colder for optimal long-term stability in research settings; short-term refrigeration at around 39°F suffices for immediate use within weeks, though freezer storage maximizes integrity across extended research timelines.
Frequently Asked Questions
How isshipped?
Orders are processed and shipped using secure, protective packaging to maintain product integrity during transit.
In what form is supplied?
Shipment is available in freeze-dried solid or liquid form.
How should be stored?
Store sealed vials protected from light, heat, and contamination in a clean laboratory environment.
What vial sizes are available ?
available in multiple vial sizes.
How to place an order?
Contact us via WhatsApp or email to get a quotation and place your order.
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