Dermorphin Peptide
Contact us for quotation
High-Potency Opioid Peptide for Advanced Neuroscience Research Dermorphin is a natural heptapeptide originally isolated from frog skin, renowned for its exceptionally high and selective affinity for $\mu$-opioid receptors. Engineered for precise pain pathway, receptor binding, and cellular signaling investigations.
Key Highlights
-
High $\mu$-Opioid Receptor Selectivity: Exhibits extraordinary binding affinity and potency specifically targeting $\mu$-opioid receptors in the central nervous system.
-
Natural Heptapeptide Structure: Features the characteristic amino acid sequence (Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2) incorporating a D-amino acid for enhanced enzymatic stability.
-
Advanced Neurobiology Applications: Widely utilized in pain modulation studies, receptor autoradiography, and opioid pharmacology research.
-
Consistent Batch Quality: Manufactured to high standards to ensure structural integrity and reliable experimental reproducibility.
Mechanism of Action
Dermorphin interacts directly with endogenous opioid systems:
-
Receptor Binding: Selectively binds to and activates $\mu$-opioid receptors located in the brain and spinal cord.
-
Signal Transduction: Inhibits adenylate cyclase activity through G-protein coupled receptor (GPCR) pathways, modulating neuronal excitability and nociceptive signaling.
-
Enzymatic Stability: The presence of D-alanine at position 2 confers increased resistance to systemic enzymatic degradation compared to naturally occurring L-peptides.
Keep lyophilized peptides sealed in their original vial, protected from light and humidity, and store at -4°F or colder for optimal long-term stability in research settings; short-term refrigeration at around 39°F suffices for immediate use within weeks, though freezer storage maximizes integrity across extended research timelines.
Frequently Asked Questions
How isshipped?
Orders are processed and shipped using secure, protective packaging to maintain product integrity during transit.
In what form is supplied?
Shipment is available in freeze-dried solid or liquid form.
How should be stored?
Store sealed vials protected from light, heat, and contamination in a clean laboratory environment.
What vial sizes are available ?
available in multiple vial sizes.
How to place an order?
Contact us via WhatsApp or email to get a quotation and place your order.
Related products
